WP1: EMF and health and development of children and adolescents – exploiting (large-scale) prospective cohorts
WP1 aims to evaluate potential effects of RF exposure on reproductive outcomes and on neurodevelopment of children and young people, exploiting existing data from large-scale European cohort studies, implementing a standardised outcome assessment of cognitive and behavioural development, and including exposure measurements for near and far-field RF.
WP2 aims to evaluate the possible association between exposure to RF and IF and the risk of brain tumours in young people and, if appropriate, to evaluate possible interaction with other potential risk factors.
WP3 consists of two main tasks to conduct novel epidemiological research on the potential health effects of occupational RF and IF exposure. The first task seeks to build upon the large, established INTEROCC study to examine associations between RF and IF exposure based on SEMs that will be derived in WP6 and risk of glioma and meningioma overall, as well as potential synergies with occupational chemical exposures. The second task seeks to conduct a register-based cohort study in Finland to examine the potential reproductive health effects of occupational IF among female cashiers and will serve as a pilot study for a potential future multinational study of cashiers.
To investigate mechanisms that may link exposure to RF and IF to behavioural and reproductive effects, as well as cancer, ageing and Alzheimer’s disease (AD) using a series of interlinked animal and cellular models and systems biology. Where appropriate, joint effects with chemical exposures will also be evaluated.
To better understand the mechanisms of the biological effects of RF and IF fields, in-vitro experiments will be conducted at the cellular and molecular levels using several novel approaches. In-vitro investigations will be complementary to in-vivo experiments, providing insights at the molecular and subcellular levels.
WP6 has three main objectives. Firstly, it will identify near- and far-field sources of RF and IF, and estimate levels of exposure in the general population. Secondly, it will use dosimetric modelling to derive novel organ specific metrics for use in epidemiological studies, for near- and far-field sources in occupational and non-occupational settings. Thirdly, it will integrate exposure across frequencies, sources, and types resulting in cumulative exposure metrics.
As an overall objective, WP7 aims to serve as the hub in which the different scientific disciplines and research groups represented in GERoNiMO are brought together to share their knowledge, to synthesize their findings (where appropriate), and thereby provide the means to further the state of the art in EMF and health research in an integrated way. As such, it will quantify potential health impacts of exposure to EMF (including IF, RF but also other frequency bands such as ELF if informative data from other complementary projects are available) in the EU27 population overall, as well as under several scenarios related to possible future trends in EMF technologies and to non-technological means of reducing exposure, and investigate uncertainties using probabilistic simulation, sensitivity analyses, and importance analysis.
WP8: Input to future risk management and communication processes and advice on non-technological means to reduce exposure
The objectives of WP8 are to synthesize the findings of GERoNiMO and translate these into inputs to risk management, to explore non-technological means for reducing exposure taking into account current and foreseeable technological trends, and to provide input on risk communication to EC policy-makers.